Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20529698 | 1.00 | PTPN22 (0.46) | PTPN22ERN1POLBHSD17B10CYP1A2 | |
| SCHEMBL30391200 | 0.82 | PTPN22 (0.42) | PTPN22ERN1POLBHSD17B10CYP1A2 | |
| SCHEMBL28497134 | 0.80 | PTPN22 (0.50) | PTPN22ERN1POLBHSD17B10CYP1A2 | |
| SCHEMBL5014197 | 0.78 | CYP1A2 (0.38) | POLBHSD17B10CYP1A2CYP2C19KDM4E | |
| SCHEMBL15274205 | 0.77 | L3MBTL1 (0.43) | HSD17B10CYP1A2KDM4EMAPTTDP1 | |
| SCHEMBL28797623 | 0.76 | PTPN22 (0.46) | PTPN22ERN1POLBHSD17B10CYP1A2 | |
| SCHEMBL15274207 | 0.76 | L3MBTL1 (0.42) | ERN1POLBHSD17B10CYP1A2KDM4E | |
| SCHEMBL28624944 | 0.75 | PTPN22 (0.48) | PTPN22ERN1POLBHSD17B10CYP1A2 | |
| SCHEMBL1470735 | 0.75 | ALDH1A1 (0.35) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E | |
| SCHEMBL29690232 | 0.75 | ALDH1A1 (0.35) | HSD17B10CYP1A2CYP2C9CYP2C19KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114671816-B | Preparation method of axial chiral aryl triazole compound | 浙江大学 | 2023-11-17 | — | — | CN | disclosed |