Sugi Predict

Sugi Predict / Compounds / SCHEMBL30697697

SCHEMBL30697697

SCHEMBL30697697

N#Cc1cccnc1SCCC(C#N)C#N

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CXCR2 P25025 1/20 0.38
▸ SLC22A12 Q96S37 1/20 0.38
▸ ALDH1A1 P00352 9/20 0.37
▸ KDM4E B2RXH2 5/20 0.37
▸ LMNA P02545 2/20 0.37
▸ HSD17B10 Q99714 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ NPC1 O15118 4/20 0.35
▸ RAB9A P51151 4/20 0.35
▸ MAOA P21397 1/20 0.35
▸ MAOB P27338 1/20 0.35
▸ HPGD P15428 8/20 0.35
▸ SMN1; SMN2 Q16637 5/20 0.34
▸ CYP2D6 P10635 3/20 0.34
▸ CYP1A2 P05177 2/20 0.34
▸ CYP2C9 P11712 2/20 0.34
▸ CYP2C19 P33261 2/20 0.34
▸ TDP1 Q9NUW8 2/20 0.34
▸ L3MBTL1 Q9Y468 2/20 0.34
▸ CYP3A4 P08684 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26119745 1.00 CXCR2 (0.38) CXCR2SLC22A12ALDH1A1KDM4ELMNA
SCHEMBL26120892 0.75 RAB9A (0.41) ALDH1A1HSD17B10HTTNPC1RAB9A
SCHEMBL26136725 0.74 CYP1A2 (0.42) LMNAMAOAMAOBCYP2D6CYP1A2
SCHEMBL15897470 0.73 MAPT (0.50) CXCR2SLC22A12ALDH1A1KDM4ELMNA
SCHEMBL26119461 0.73 KDM4E (0.31) ALDH1A1KDM4ELMNAHSD17B10HTT
SCHEMBL7028044 0.72 SLC22A12 (0.41) CXCR2SLC22A12ALDH1A1KDM4ELMNA
SCHEMBL3605491 0.72 ALDH1A1 (0.55) CXCR2SLC22A12ALDH1A1KDM4EHSD17B10
SCHEMBL16297352 0.72 TP53 (0.46) CXCR2SLC22A12ALDH1A1KDM4ELMNA
SCHEMBL30968888 0.72 HPGD (0.42) CXCR2SLC22A12ALDH1A1KDM4ELMNA
SCHEMBL30697709 0.71 CYP2D6 (0.45) CXCR2SLC22A12ALDH1A1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250243169-A1 PROCESS FOR THE PREPARATION OF DIVERSELY SUBSTITUTED CYANOCYCLOPROPYL-HETEROCYCLES OR ARENES SYNGENTA CROP PROTECTION AG (CH) 2025-07-31 — — US disclosed
EP-4504706-A1 PROCESS FOR THE PREPARATION OF DIVERSELY SUBSTITUTED CYANOCYCLOPROPYL - HETEROARENES OR ARENES Syngenta Crop Protection AG (CH) 2025-02-12 — — EP disclosed
CN-119032081-A Process for preparing various substituted cyanocyclopropyl-heteroarenes or arenes 先正达农作物保护股份公司 2024-11-26 — — CN disclosed
WO-2023194496-A1 PROCESS FOR THE PREPARATION OF DIVERSELY SUBSTITUTED CYANOCYCLOPROPYL - HETEROARENES OR ARENES SYNGENTA CROP PROTECTION AG (CH) 2023-10-12 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250243169-A1 PROCESS FOR THE PREPARATION OF DIVERSELY SUBSTITUTED CYANOCYCLOPROPYL-HETEROCYCLES OR ARENES CYCS, CCNE1, CCNT1 CXCR2 255/4885SLC22A12 2017/4885ALDH1A1 804/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.