Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.49 |
| ▸ | PPARG | P37231 | 2/20 | 0.49 |
| ▸ | NCOA2 | Q15596 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8776813 | 0.86 | TSHR (0.61) | ALDH1A1CYP2C9KMT2AMEN1POLB | |
| SCHEMBL8776779 | 0.76 | KDM4E (0.46) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 | |
| SCHEMBL1819828 | 0.76 | ALDH1A1 (0.51) | ALDH1A1KMT2AMEN1L3MBTL1POLB | |
| SCHEMBL8776755 | 0.76 | TSHR (0.58) | ALDH1A1CYP2C9L3MBTL1CXCR2TDP1 | |
| SCHEMBL15897470 | 0.75 | MAPT (0.50) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 | |
| SCHEMBL8776853 | 0.75 | ALDH1A1 (0.64) | ALDH1A1CYP2C9KMT2AMEN1POLB | |
| SCHEMBL1827394 | 0.75 | ALDH1A1 (0.59) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 | |
| SCHEMBL5953902 | 0.75 | ALDH1A1 (0.64) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 | |
| SCHEMBL8883167 | 0.75 | ALDH1A1 (0.59) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 | |
| SCHEMBL8115003 | 0.75 | ALDH1A1 (0.59) | ALDH1A1CYP2C9KMT2AMEN1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | claimed |
| US-20080139817-A1 | Process For Producing 2-(Phenyl Methyl Thio)-3-Pyridine Carboxylic Acid | JUBILANT ORGANOSYS LIMITED (IN) | 2008-06-12 | — | — | US | claimed |
| WO-2005097748-A1 | PROCESS FOR PRODUCING 2-(PHENYL METHYL THIO)-3-PYRIDINE CARBOXYLIC ACID | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-20 | — | — | WO | claimed |
| CN-106928134-B | A kind of preparation facilities and synthetic method of nicosulfuron intermediate | 山东理工大学 | 2019-07-16 | — | — | CN | disclosed |
| CN-106928134-A | The preparation facilities and synthetic method of a kind of nicosulfuron intermediate | 山东理工大学 | 2017-07-07 | — | — | CN | disclosed |
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | disclosed |
| US-7745631-B2 | Reacting 2-chloro-3-cyanopyridine with benzyl mercaptan in the presence of a sodium carbonate and an aprotic solvent; hydrolyzing resulting intermediate; no need for purification | JUBILANT ORGANOSYS LIMITED (IN) | 2010-06-29 | — | — | US | disclosed |
| US-20080139817-A1 | Process For Producing 2-(Phenyl Methyl Thio)-3-Pyridine Carboxylic Acid | JUBILANT ORGANOSYS LIMITED (IN) | 2008-06-12 | — | — | US | disclosed |
| US-20080139817-A1 | Process For Producing 2-(Phenyl Methyl Thio)-3-Pyridine Carboxylic Acid | JUBILANT ORGANOSYS LIMITED (IN) | 2008-06-12 | — | — | US | disclosed |
| WO-2005097748-A1 | PROCESS FOR PRODUCING 2-(PHENYL METHYL THIO)-3-PYRIDINE CARBOXYLIC ACID | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-20 | — | — | WO | disclosed |
| WO-2005097748-A1 | PROCESS FOR PRODUCING 2-(PHENYL METHYL THIO)-3-PYRIDINE CARBOXYLIC ACID | JUBILANT ORGANOSYS LIMITED (IN) | 2005-10-20 | — | — | WO | disclosed |