SCHEMBL3069941

SCHEMBL3069941

NCCNc1ccc2c(=O)[nH][nH]c(=O)c2c1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ PIK3CD O00329 1/20 0.47
▸ KDM4E B2RXH2 2/20 0.43
▸ TDP1 Q9NUW8 1/20 0.43
▸ PARP15 Q460N3 5/20 0.39
▸ PARP10 Q53GL7 5/20 0.39
▸ HTR6 P50406 5/20 0.39
▸ DAO P14920 1/20 0.37
▸ GLA P06280 1/20 0.37
▸ GAA P10253 1/20 0.37
▸ MAPT P10636 1/20 0.37
▸ HSD17B10 Q99714 1/20 0.37
▸ PARP3 Q9Y6F1 1/20 0.36
▸ FERMT2 Q96AC1 1/20 0.35
▸ AR P10275 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3088454 0.90 PIK3CD (0.51) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL3090005 0.89 PIK3CD (0.53) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL5917486 0.87 KDM4E (0.52) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL6953743 0.79 PIK3CD (0.40) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL438637 0.79 AR (0.47) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL11262249 0.76 PIK3CD (0.36) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL5179312 0.76 PIK3CD (0.40) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL3277310 0.76 HSD17B10 (0.46) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL8057185 0.75 CA12 (0.44) PIK3CDKDM4ETDP1PARP15PARP10
SCHEMBL6955664 0.74 IP6K1 (0.43) PIK3CDKDM4EAR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230272457-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE ILLUMINA, INC. 2023-08-31 — — US disclosed
US-11629373-B2 Compositions, systems, and methods for detecting the presence of polymer subunits using chemiluminescence ILLUMINA, INC. (US) 2023-04-18 — — US disclosed
US-11592442-B2 Control marker for implementing analysis methods on spots BIO-RAD EUROPE GMBH (CH) 2023-02-28 — — US disclosed
US-20220137036-A1 CONTROLS FOR IMPLEMENTING MULTIPLEX ANALYSIS METHODS BIO-RAD EUROPE GMBH (CH) 2022-05-05 — — US disclosed
US-11226331-B2 Controls for implementing multiplex analysis methods BIO-RAD EUROPE GMBH (CH) 2022-01-18 — — US disclosed
CN-106415271-B Controls for performing multiplex assay methods 伯乐欧洲有限公司 2021-08-10 — — CN disclosed
US-20210164973-A1 CONTROL MARKER FOR IMPLEMENTING ANALYSIS METHODS ON SPOTS BIO-RAD EUROPE GMBH (CH) 2021-06-03 — — US disclosed
CN-106415272-B Use of absorbent particles for improving signal detection in analytical methods 伯乐欧洲有限公司 2021-05-28 — — CN disclosed
US-10921318-B2 Control marker for implementing analysis methods on spots BIO-RAD EUROPE GMBH (CH) 2021-02-16 — — US disclosed
US-20200318167-A1 COMPOSITIONS, SYSTEMS, AND METHODS FOR DETECTING THE PRESENCE OF POLYMER SUBUNITS USING CHEMILUMINESCENCE ILLUMINA, INC. 2020-10-08 — — US disclosed
EP-2468765-A1 Multimer of extracellular domain of cell surface functional molecule ONO Pharmaceutical Co., Ltd. (JP) 2012-06-27 — — EP disclosed
US-20110318373-A1 IMMUNOSUPPRESSION MODULATING COMPOUNDS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2011-12-29 — — US disclosed
WO-2011161699-A2 IMMUNOSUPPRESSION MODULATING COMPOUNDS AURIGENE DISCOVERY TECHNOLOGIES LIMITED (IN) 2011-12-29 — — WO disclosed
US-20110052448-A1 SPECIFIC COMPONENT MEASURING METHOD BY SPECTRAL MEASUREMENT WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2011-03-03 — — US disclosed
US-7795034-B2 Specific component measuring method by spectral measurement WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2010-09-14 — — US disclosed
US-20090305950-A1 MULTIMER OF EXTRACELLULAR DOMAIN OF CELL SURFACE FUNCTIONAL MOLECULE ONO PHARMACEUTICAL CO., LTD. (JP) 2009-12-10 — — US disclosed
EP-1997887-A1 MULTIMER OF EXTRACELLULAR DOMAIN OF CELL SURFACE FUNCTIONAL MOLECULE Kyoto University (JP) 2008-12-03 — — EP disclosed
US-20060170914-A1 Specific component measuring method by spectral measurement WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2006-08-03 — — US disclosed
US-20060073526-A1 Antibodies, assay method by using them and judgment method for pancreas cancer WAKO PURE CHEMICAL INDUSTRIES, LTD 2006-04-06 — — US disclosed
EP-1643240-A1 SPECIFIC COMPONENT MEASURING METHOD BY SPECTRAL MEASUREMENT Wako Pure Chemical Industries, Ltd. (JP) 2006-04-05 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110318373-A1 IMMUNOSUPPRESSION MODULATING COMPOUNDS CD274, PDCD1, PDCD1LG2 PIK3CD 596/4885KDM4E 2955/4885TDP1 2920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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