Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 9/20 | 0.36 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.33 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6955664 | 0.81 | IP6K1 (0.43) | PIK3CDKDM4EIP6K1 | |
| SCHEMBL3277310 | 0.80 | HSD17B10 (0.46) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL3069941 | 0.79 | PIK3CD (0.47) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL438637 | 0.79 | AR (0.47) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL3088454 | 0.77 | PIK3CD (0.51) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL3090005 | 0.76 | PIK3CD (0.53) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL8057185 | 0.75 | CA12 (0.44) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL5917486 | 0.74 | KDM4E (0.52) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL11262249 | 0.73 | PIK3CD (0.36) | PIK3CDKDM4EHSD17B10PARP15PARP10 | |
| SCHEMBL7070839 | 0.72 | KDM4E (0.50) | PIK3CDKDM4EHSD17B10PARP15PARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8183060-B2 | comprises biotin covalently attached to a polymer that has monosaccharide or amino acid as a constituent monomer covalently attached to a luminescent substance (cyanoisoindoles, luminols, and acridinium esters); detecting a target substance at high sensitivity | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 2012-05-22 | — | — | US | disclosed |