Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CASR | P41180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL9622388 | 0.89 | ELANE (0.40) | ARKDM4EHSD17B10ALDH1A1POLB | |
| SCHEMBL6953743 | 0.79 | PIK3CD (0.40) | KDM4EHSD17B10PIK3CDTDP1PARP15 | |
| SCHEMBL3069941 | 0.79 | PIK3CD (0.47) | ARKDM4EHSD17B10PIK3CDTDP1 | |
| SCHEMBL7070839 | 0.79 | KDM4E (0.50) | ARKDM4EHSD17B10PIK3CDTDP1 | |
| SCHEMBL8057185 | 0.77 | CA12 (0.44) | KDM4EHSD17B10ALDH1A1PIK3CDTDP1 | |
| SCHEMBL3088454 | 0.76 | PIK3CD (0.51) | ARKDM4EHSD17B10PIK3CDTDP1 | |
| SCHEMBL5179312 | 0.76 | PIK3CD (0.40) | ARKDM4EHSD17B10ELANEPIK3CD | |
| SCHEMBL3090005 | 0.75 | PIK3CD (0.53) | ARKDM4EHSD17B10ALDH1A1PIK3CD | |
| SCHEMBL3277310 | 0.75 | HSD17B10 (0.46) | KDM4EHSD17B10ALDH1A1POLBPIK3CD | |
| SCHEMBL6955664 | 0.74 | IP6K1 (0.43) | ARKDM4EPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2596119-A2 | METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS | Advanced Cell Technology, Inc. (US) | 2013-05-29 | — | — | EP | claimed |
| WO-2012012803-A2 | METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS | ADVANCED CELL TECHNOLOGY, INC. (US) | 2012-01-26 | — | — | WO | claimed |
| US-6322992-B1 | CONTACTING FLUID SAMPLE SUSPECTED OF CONTAINING SPECIFIC BINDING LIGAND WITH AN ANALYTIC ELEMENT CONTAINING VANADIUM BROMOPEROXIDASE-LABELED LIGAND OR ANALOG, AND IMMOBILIZED RECEPTOR THAT BINDS LIGAND OR ANALOG; APPLYING WASH SOLUTION | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. | 2001-11-27 | — | — | US | claimed |
| EP-0848819-B1 | ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME | ORTHO CLINICAL DIAGNOSTICS INC (US) | 2000-04-26 | — | — | EP | claimed |
| EP-0892855-A1 | USE OF VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME FOR CHEMILUMINESCENT SYSTEMS: TEST KITS AND ANALYTICAL METHODS | Ortho-Clinical Diagnostics, Inc. (US) | 1999-01-27 | — | — | EP | claimed |
| US-5811253-A | Use of vanadium bromoperoxidase as a signal-generating enzyme for chemiluminescent systems: test kits and analytical methods | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1998-09-22 | — | — | US | claimed |
| EP-0848819-A1 | ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME | Ortho-Clinical Diagnostics, Inc. (US) | 1998-06-24 | — | — | EP | claimed |
| WO-1997009447-A1 | USE OF VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME FOR CHEMILUMINESCENT SYSTEMS: TEST KITS AND ANALYTICAL METHODS | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-03-13 | — | — | WO | claimed |
| WO-1997009619-A1 | ANALYTICAL ELEMENT AND METHOD FOR THE DETERMINATION OF A SPECIFIC BINDING LIGAND USING A VANADIUM BROMOPEROXIDASE AS A SIGNAL-GENERATING ENZYME | JOHNSON & JOHNSON CLINICAL DIAGNOSTICS, INC. (US) | 1997-03-13 | — | — | WO | claimed |
| US-5372931-A | Use of 4'-hydroxy- and 4'-alkoxy-substituted electron transfer agents in compositions, elements, test kits and analytical methods | EASTMAN KODAK COMPANY (US) | 1994-12-13 | — | — | US | claimed |
| US-5279940-A | Containing 2,3-dihydro-1,4-phthalazinedione, cationic surfactant, and 4*-hydroxyacetanilide | EASTMAN KODAK COMPANY (US) | 1994-01-18 | — | — | US | claimed |
| EP-4325210-A1 | COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE | FUJIFILM Corporation (JP) | 2024-02-21 | — | — | EP | disclosed |
| US-20240043742-A1 | COMPOSITION, STABILIZATION METHOD, METHOD FOR MEASURING AMOUNT OF LUMINESCENCE, AND STABILIZER FOR LUMINESCENT SUBSTRATE | FUJIFILM CORPORATION (JP) | 2024-02-08 | — | — | US | disclosed |
| US-11879148-B2 | Methods for detection, determination, and activity measurement of peroxidase based on chemiluminescence | KYOTO LUMINOUS SCIENCE LABORATORY (JP) | 2024-01-23 | — | — | US | disclosed |
| WO-2009055794-A1 | METHOD AND COMPOSITIONS FOR POLYMER NANOCARRIERS CONTAINING THERAPEUTIC MOLECULES | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2009-04-30 | — | — | WO | disclosed |
| US-5279940-A | Containing 2,3-dihydro-1,4-phthalazinedione, cationic surfactant, and 4*-hydroxyacetanilide | EASTMAN KODAK COMPANY (US) | 1994-01-18 | — | — | US | disclosed |
| US-5206149-A | Reaction of peroxidase, oxidant, luminol and 2-hydroxy-9-fluorenone enhancer; chemiluminescence | TORAY INDUSTRIES, INC. (JP) | 1993-04-27 | — | — | US | disclosed |
| US-5106732-A | Using oxazole or thiazole derivative | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| EP-0384271-A2 | Method for enhancement of chemiluminescence | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-08-29 | — | — | EP | disclosed |
| EP-0134707-B1 | METHOD OF ASSAYING THE ACTIVITY OF CELLS | TORAY INDUSTRIES, INC. (JP) | 1988-12-07 | — | — | EP | disclosed |