Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CASR | P41180 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | PARP15 | Q460N3 | 7/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 7/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | BRAF | P15056 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL438637 | 0.77 | AR (0.47) | CASRPIK3CDKDM4EALDH1A1PARP15 | |
| SCHEMBL3069941 | 0.75 | PIK3CD (0.47) | PIK3CDKDM4EPARP15PARP10HSD17B10 | |
| SCHEMBL6953743 | 0.75 | PIK3CD (0.40) | PIK3CDKDM4EPARP15PARP10HSD17B10 | |
| SCHEMBL3090005 | 0.71 | PIK3CD (0.53) | PIK3CDKDM4EALDH1A1PARP15PARP10 | |
| SCHEMBL99646 | 0.71 | CA12 (0.65) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL3277310 | 0.71 | HSD17B10 (0.46) | PIK3CDKDM4EALDH1A1RAB9APARP15 | |
| SCHEMBL7070839 | 0.71 | KDM4E (0.50) | PIK3CDKDM4EPARP15PARP10HSD17B10 | |
| SCHEMBL5775239 | 0.70 | CA12 (0.50) | CA12CA1CA2CA9CASR | |
| SCHEMBL11045211 | 0.70 | CASP3 (0.53) | CA12CA1CA2CA9KDM4E | |
| SCHEMBL13144114 | 0.70 | KDM4E (0.59) | KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0516948-B1 | Chemiluminescent method and compositions | LUMIGEN INC (US) | 2000-05-31 | — | — | EP | claimed |
| EP-0516948-B1 | Chemiluminescent method and compositions | LUMIGEN INC (US) | 2000-05-31 | — | — | EP | disclosed |
| EP-0516948-A1 | Chemiluminescent method and compositions | LUMIGEN, INC. (US) | 1992-12-09 | — | — | EP | disclosed |