Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 4/20 | 0.40 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 5/20 | 0.32 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699921 | 1.00 | LOXL2 (0.40) | LOXL2ABHD6MGLLDGAT2 | |
| SCHEMBL30700468 | 0.88 | LOXL2 (0.38) | LOXL2ABHD6MGLL | |
| SCHEMBL30700230 | 0.88 | LOXL2 (0.38) | LOXL2ABHD6MGLL | |
| SCHEMBL30700094 | 0.88 | LOXL2 (0.38) | LOXL2ABHD6MGLL | |
| SCHEMBL30700529 | 0.81 | LOXL2 (0.38) | LOXL2ABHD6MGLLDGAT2 | |
| SCHEMBL30700595 | 0.79 | GPR119 (0.37) | LOXL2 | |
| SCHEMBL25301218 | 0.78 | LOXL2 (0.47) | LOXL2ABHD6MGLLDGAT2 | |
| SCHEMBL30013052 | 0.77 | MGLL (0.55) | LOXL2ABHD6MGLL | |
| SCHEMBL27154197 | 0.77 | MGLL (0.55) | LOXL2ABHD6MGLL | |
| SCHEMBL25324473 | 0.77 | LOXL2 (0.40) | LOXL2ABHD6MGLLDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |