Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 8/20 | 0.37 |
| ▸ | LIPE | Q05469 | 4/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 5/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700450 | 0.84 | GPR119 (0.38) | GPR119LIPELOXL2HCRTR1 | |
| SCHEMBL30700784 | 0.80 | GPR119 (0.37) | GPR119LIPELOXL2HCRTR1HCRTR2 | |
| SCHEMBL30700008 | 0.79 | LOXL2 (0.40) | LOXL2 | |
| SCHEMBL30699921 | 0.79 | LOXL2 (0.40) | LOXL2 | |
| SCHEMBL30700376 | 0.79 | ABHD6 (0.39) | GPR119LOXL2HCRTR1 | |
| SCHEMBL30700336 | 0.77 | ENPP2 (0.36) | GPR119LIPE | |
| SCHEMBL25326437 | 0.76 | GPR119 (0.35) | GPR119LOXL2HCRTR1HCRTR2 | |
| SCHEMBL30553320 | 0.76 | GPR119 (0.35) | GPR119LOXL2HCRTR1HCRTR2 | |
| SCHEMBL31308764 | 0.75 | GPR119 (0.50) | GPR119LOXL2 | |
| SCHEMBL30700787 | 0.75 | GPR119 (0.50) | GPR119LOXL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |