Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | VNN1 | O95497 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700054 | 0.87 | MGLL (0.40) | MGLLIDO1 | |
| SCHEMBL30700566 | 0.83 | RORC (0.36) | MGLL | |
| SCHEMBL30700087 | 0.78 | MGLL (0.43) | MGLLIDO1 | |
| SCHEMBL30699870 | 0.78 | MGLL (0.43) | MGLLIDO1 | |
| SCHEMBL30700094 | 0.76 | LOXL2 (0.38) | MGLLIDO1 | |
| SCHEMBL30700230 | 0.76 | LOXL2 (0.38) | MGLLIDO1 | |
| SCHEMBL30700468 | 0.76 | LOXL2 (0.38) | MGLLIDO1 | |
| SCHEMBL30700071 | 0.74 | MGLL (0.37) | MGLL | |
| SCHEMBL30700049 | 0.74 | MGLL (0.37) | MGLL | |
| SCHEMBL30700903 | 0.74 | MGLL (0.40) | MGLLIDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |