Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 6/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.35 |
| ▸ | APLNR | P35414 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700071 | 1.00 | MGLL (0.37) | MGLLADRA2CAPLNR | |
| SCHEMBL30700283 | 0.85 | MGLL (0.37) | MGLL | |
| SCHEMBL30700235 | 0.85 | MGLL (0.36) | MGLL | |
| SCHEMBL30700328 | 0.85 | MGLL (0.36) | MGLL | |
| SCHEMBL30700903 | 0.79 | MGLL (0.40) | MGLL | |
| SCHEMBL30700677 | 0.79 | MGLL (0.40) | MGLL | |
| SCHEMBL30700087 | 0.78 | MGLL (0.43) | MGLL | |
| SCHEMBL30699870 | 0.78 | MGLL (0.43) | MGLL | |
| SCHEMBL30700238 | 0.77 | ADRA2C (0.35) | MGLLADRA2CAPLNR | |
| SCHEMBL30700566 | 0.76 | RORC (0.36) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| CN-119301113-A | Novel heterocyclic carbonyl cyclic compounds as MAGL inhibitors | 豪夫迈·罗氏有限公司 | 2025-01-10 | — | — | CN | disclosed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |