Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.36 |
| ▸ | MAPK7 | Q13164 | 2/20 | 0.35 |
| ▸ | KIT | P10721 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30699861 | 0.93 | MGLL (0.40) | MGLLEPHX2KIT | |
| SCHEMBL25324067 | 0.92 | MGLL (0.41) | MGLLEPHX2KIT | |
| SCHEMBL30700373 | 0.88 | MGLL (0.43) | MGLLEPHX2 | |
| SCHEMBL30700050 | 0.85 | MGLL (0.41) | MGLLMAPK7 | |
| SCHEMBL30700398 | 0.85 | MGLL (0.41) | MGLL | |
| SCHEMBL30700187 | 0.83 | MGLL (0.43) | MGLLEGLN1 | |
| SCHEMBL30700274 | 0.83 | MGLL (0.41) | MGLL | |
| SCHEMBL30700280 | 0.82 | MGLL (0.37) | MGLLEPHX2 | |
| SCHEMBL30700216 | 0.81 | EPHX2 (0.38) | MGLLEPHX2 | |
| SCHEMBL30700516 | 0.81 | MGLL (0.44) | MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |