Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TEAD1 | P28347 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700801 | 0.82 | MGLL (0.47) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL30700465 | 0.82 | MGLL (0.47) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL27288877 | 0.82 | MGLL (0.47) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL30699948 | 0.82 | MGLL (0.43) | MGLLTEAD1MCHR1SCN9AF2R | |
| SCHEMBL30700318 | 0.80 | MGLL (0.45) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL30699918 | 0.80 | MGLL (0.41) | MGLLTEAD1MCHR1SCN9AF2R | |
| SCHEMBL30700088 | 0.80 | MGLL (0.41) | MGLLTEAD1MCHR1SCN9AF2R | |
| SCHEMBL30700370 | 0.79 | FAAH (0.44) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL30700371 | 0.79 | ENPP2 (0.43) | MGLLGAATDP1CYP1A2CYP3A4 | |
| SCHEMBL30700512 | 0.79 | FAAH (0.44) | MGLLGAATDP1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |