Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | LIPE | Q05469 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700725 | 0.90 | AKR1C3 (0.46) | MEN1KMT2AAKR1C3SCN9ALIPE | |
| SCHEMBL30700656 | 0.83 | CNR1 (0.46) | KMT2AAKR1C3LMNAHTTSMN1; SMN2 | |
| SCHEMBL30700417 | 0.82 | MGLL (0.44) | AKR1C3DPP4EPHX2SCN9ALMNA | |
| SCHEMBL30700774 | 0.81 | AKR1C3 (0.42) | MEN1KMT2AAKR1C3LMNAHTT | |
| SCHEMBL30700670 | 0.80 | AKR1C3 (0.42) | AKR1C3HTR2B | |
| SCHEMBL30700080 | 0.79 | MGLL (0.40) | EPHX2HTR2B | |
| SCHEMBL30699969 | 0.78 | KIT (0.45) | AKR1C3DPP4HDAC8 | |
| SCHEMBL25323642 | 0.78 | MEN1 (0.43) | MEN1KMT2AAKR1C3DPP4EPHX2 | |
| SCHEMBL25325330 | 0.77 | DPP4 (0.42) | MEN1KMT2AAKR1C3DPP4EPHX2 | |
| SCHEMBL30699974 | 0.77 | LIPE (0.42) | SCN9ALIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |