Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30700162 | 0.90 | TGFBR1 (0.44) | MGLLALDH1A1AKR1C3LMNAPOLB | |
| SCHEMBL30700144 | 0.87 | MGLL (0.49) | MGLLALDH1A1LMNAPKM | |
| SCHEMBL30700706 | 0.85 | PSEN1 (0.41) | MGLLALDH1A1AKR1C3LMNAPOLB | |
| SCHEMBL30700856 | 0.82 | MEN1 (0.43) | AKR1C3LMNAEPHX2DPP4SCN9A | |
| SCHEMBL30700719 | 0.79 | TSHR (0.47) | ALDH1A1AKR1C3L3MBTL1TDP1GAA | |
| SCHEMBL25301386 | 0.77 | MGLL (0.57) | MGLLALDH1A1LMNAPOLBEPHX2 | |
| SCHEMBL30700193 | 0.77 | PSEN1 (0.43) | AKR1C3LMNADPP4KCNH2DPP7 | |
| SCHEMBL25326454 | 0.76 | MGLL (0.43) | MGLLALDH1A1LMNAPOLBEPHX2 | |
| SCHEMBL30699920 | 0.75 | HTR1A (0.44) | EPHX2GAA | |
| SCHEMBL30699959 | 0.74 | ENPP2 (0.39) | MGLLEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543870-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2025-04-30 | — | — | EP | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | claimed |
| WO-2023247670-A1 | NEW HETEROCYCLIC-CARBONYL-CYCLIC COMPOUNDS AS MAGL INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2023-12-28 | — | — | WO | disclosed |