SCHEMBL30701161

SCHEMBL30701161

CCCOc1cc(CBr)cc(OC)n1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
LMNA P02545 2/20 0.35
MAPT P10636 2/20 0.35
HTT P42858 1/20 0.35
ATM Q13315 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
LOX P28300 1/20 0.35
LOXL2 Q9Y4K0 1/20 0.35
ADORA3 P0DMS8 4/20 0.35
ADORA2A P29274 2/20 0.35
MEN1 O00255 1/20 0.35
GLA P06280 1/20 0.35
POLB P06746 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
ALOX5 P09917 1/20 0.34
ENPP1 P22413 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19330187 1.00 ALDH1A1 (0.35) ALDH1A1LMNAMAPTHTTATM
SCHEMBL19353931 0.86 SMN1; SMN2 (0.39) ALDH1A1MAPTHTTLOXLOXL2
SCHEMBL3444983 0.85 ALDH1A1 (0.42) ALDH1A1LMNAHTTTDP1LOX
SCHEMBL19330247 0.83 ALDH1A1 (0.38) ALDH1A1LMNAMAPTHTTATM
SCHEMBL19330128 0.77 SMN1; SMN2 (0.42) ALDH1A1LMNAMAPTADORA2ATSHR
SCHEMBL13713702 0.77 LMNA (0.44) ALDH1A1LMNAMAPTHTTATM
SCHEMBL31403787 0.75 ALDH1A1 (0.45) ALDH1A1LMNAMAPTHTTATM
SCHEMBL19330352 0.75 ALDH1A1 (0.51) ALDH1A1LMNAMAPTHTTATM
SCHEMBL12093701 0.74 HTR7 (0.46) ALDH1A1LMNAMAPTHTTATM
SCHEMBL20768215 0.74 SMN1; SMN2 (0.40) ALDH1A1LMNAMAPTHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109069514-B Antibacterial compound and application thereof 结核病药物开发全球联盟公司 2023-12-29 CN disclosed