Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPPL1 | O15357 | 3/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | MAP4K3 | Q8IVH8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HTR2B | P41595 | 1/20 | 0.36 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30701913 | 0.82 | INPPL1 (0.48) | INPPL1SLC6A2SLC6A4SLC6A3MAP4K3 | |
| SCHEMBL30701936 | 0.76 | INPPL1 (0.58) | INPPL1MAP4K3SRC | |
| SCHEMBL30701925 | 0.71 | INPPL1 (0.82) | INPPL1MAP4K3 | |
| Hydrochloric Acid SCHEMBL30701912 | 0.70 | INPPL1 (0.81) | INPPL1MAP4K3 | |
| SCHEMBL23411539 | 0.69 | HTR6 (0.47) | SLC6A2SLC6A4SLC6A3HTR6USP1 | |
| SCHEMBL29892599 | 0.69 | HTR6 (0.47) | SLC6A2SLC6A4SLC6A3HTR6USP1 | |
| SCHEMBL23410958 | 0.68 | HTR3A (0.42) | USP1 | |
| SCHEMBL23411312 | 0.65 | HTR2C (0.50) | HTR6USP1HTR2C | |
| SCHEMBL29891790 | 0.65 | HTR2C (0.50) | HTR6USP1HTR2C | |
| Hydrochloric Acid SCHEMBL16827834 | 0.64 | NPC1 (0.38) | USP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4554936-A1 | CRIZOTINIB ANALOGUES AS SHIP1 INHIBITORS USEFUL TO TREAT ALZHEINER'S DISEASES | The Trustees of Indiana University (US) | 2025-05-21 | — | — | EP | disclosed |
| WO-2024015759-A1 | CRIZOTINIB ANALOGUES AS SHIP1 INHIBITORS USEFUL TO TREAT ALZHEINER'S DISEASES | THE TRUSTEES OF INDIANA UNIVERSITY (US) | 2024-01-18 | — | — | WO | disclosed |