Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.33 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27192364 | 1.00 | ALOX15 (0.38) | ALOX15HTTKITFLT3NTRK3 | |
| SCHEMBL30702067 | 0.83 | ALDH1A1 (0.36) | HTTCYP1A2CYP2A6LMNANPSR1 | |
| SCHEMBL27192431 | 0.83 | ALDH1A1 (0.36) | HTTCYP1A2CYP2A6LMNANPSR1 | |
| SCHEMBL14658340 | 0.82 | ADRA2A (0.39) | PLGCYP1A2CYP3A4CYP2C19LMNA | |
| SCHEMBL27191888 | 0.81 | PLG (0.42) | PLGPLAUPLATCYP1A2CYP3A4 | |
| SCHEMBL30702054 | 0.80 | SLC22A12 (0.34) | GAA | |
| SCHEMBL27192024 | 0.80 | CYP11B1 (0.47) | PLAUCYP1A2CYP3A4CYP2C19CYP2A6 | |
| SCHEMBL27191769 | 0.80 | SLC22A12 (0.34) | GAA | |
| SCHEMBL30702057 | 0.80 | CYP11B1 (0.47) | PLAUCYP1A2CYP3A4CYP2C19CYP2A6 | |
| SCHEMBL30701997 | 0.78 | CYP11B2 (0.35) | HTTLMNAKMT2ARAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565574-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |