Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR5A | P47898 | 8/20 | 0.61 |
| ▸ | HTR1A | P08908 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.57 |
| ▸ | DRD3 | P35462 | 1/20 | 0.57 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.54 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29133438 | 1.00 | HTR5A (0.61) | HTR5AHTR1ADRD2DRD3KCNH2 | |
| SCHEMBL29133409 | 0.89 | HTR5A (0.64) | HTR5ADRD2DRD3MAOB | |
| SCHEMBL30704357 | 0.89 | HTR5A (0.64) | HTR5ADRD2DRD3MAOB | |
| SCHEMBL29133426 | 0.79 | HTR5A (0.65) | HTR5A | |
| SCHEMBL30704343 | 0.78 | HTR5A (0.64) | HTR5AHTR1ADRD2DRD3 | |
| SCHEMBL29133417 | 0.77 | MAOA (0.68) | HTR5AHTR1ADRD2DRD3MAOB | |
| SCHEMBL30704366 | 0.77 | MAOA (0.68) | HTR5AHTR1ADRD2DRD3MAOB | |
| SCHEMBL30704344 | 0.77 | HTR5A (0.61) | HTR5AHTR1ADRD2DRD3 | |
| SCHEMBL30704360 | 0.75 | HTR5A (0.65) | HTR5A | |
| SCHEMBL30704333 | 0.74 | HTR5A (0.66) | HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |