Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 6/20 | 0.60 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.60 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.60 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.60 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.60 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.60 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.60 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.60 |
| ▸ | APAF1 | O14727 | 1/20 | 0.49 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD1 | P21728 | 1/20 | 0.49 |
| ▸ | DRD5 | P21918 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30704348 | 0.85 | ACHE (0.67) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL30704375 | 0.85 | ACHE (0.60) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL30704338 | 0.82 | ACHE (0.70) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL30704370 | 0.81 | SIGMAR1 (0.70) | ACHESIGMAR1KDM4EALDH1A1 | |
| SCHEMBL30704364 | 0.79 | ACHE (0.54) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL3724766 | 0.79 | ACHE (0.86) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL2246410 | 0.78 | ACHE (0.88) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL2189750 | 0.77 | ACHE (0.79) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL2188478 | 0.75 | ACHE (0.84) | ACHEGRIN1GRIN2AGRIN2BGRIN2D | |
| SCHEMBL2188030 | 0.75 | ACHE (0.76) | ACHEGRIN1GRIN2AGRIN2BGRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | claimed |
| CN-117327065-A | Carbazole derivatives as dopamine D2/3 receptor modulators | 北京大学 | 2024-01-02 | — | — | CN | disclosed |