Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 11/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.50 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | TOP1 | P11387 | 1/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.43 |
| ▸ | TERT | O14746 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27354638 | 1.00 | TTR (0.55) | TTRMAPTHTTPTPRCAPAF1 | |
| SCHEMBL27354628 | 0.84 | EGFR (0.49) | MAPTHTTPTPRCAPAF1ALDH1A1 | |
| SCHEMBL30704442 | 0.84 | EGFR (0.49) | MAPTHTTPTPRCAPAF1ALDH1A1 | |
| SCHEMBL12766811 | 0.81 | NTRK1 (0.54) | MAPTALDH1A1NTRK1PLK3RAB9A | |
| SCHEMBL11768754 | 0.76 | NTRK1 (0.74) | MAPTHTTAPAF1ALDH1A1NTRK1 | |
| SCHEMBL30704422 | 0.76 | NTRK1 (0.74) | MAPTHTTAPAF1ALDH1A1NTRK1 | |
| SCHEMBL71110 | 0.72 | TTR (0.68) | TTRMAPTHTTALDH1A1RAB9A | |
| SCHEMBL2495022 | 0.72 | TERT (0.54) | MAPTHTTALDH1A1NTRK1PLK3 | |
| SCHEMBL1222307 | 0.72 | TTR (0.78) | TTRMAPTHTTALDH1A1RAB9A | |
| SCHEMBL6176954 | 0.71 | KDM4E (0.68) | TTRMAPTHTTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543856-A1 | BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 | Asha Therapeutics LLC (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249965-A1 | BENZOCARBAZOLE DERIVATIVES AS INHIBITORS OF DRP1 | ASHA THERAPEUTICS LLC (US) | 2023-12-28 | — | — | WO | disclosed |