SCHEMBL3070445

SCHEMBL3070445

OC(I)c1cccc(I)c1I

nearest known ligand 0.31

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31
LMNA P02545 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
GABRA1 P14867 1/20 0.31
HPGD P15428 1/20 0.31
TSHR P16473 1/20 0.31
GABRB1 P18505 1/20 0.31
GABRG2 P18507 1/20 0.31
PTGS1 P23219 1/20 0.31
SLC6A2 P23975 1/20 0.31
HTR2C P28335 1/20 0.31
GABRB3 P28472 1/20 0.31
GABRA5 P31644 1/20 0.31
GABRA3 P34903 1/20 0.31
HTR2B P41595 1/20 0.31
GABRA2 P47869 1/20 0.31
GABRB2 P47870 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28449368 0.79 GABRA1 (0.39) FAAHCA1CA2LMNACYP1A2
SCHEMBL29161089 0.76
SCHEMBL2371297 0.76 ALDH1A1 (0.32) CYP1A2
SCHEMBL7147429 0.76 TAAR1 (0.38) LMNACYP3A4HPGDTSHRBLM
SCHEMBL29406382 0.73 GABRA1 (0.48) FAAHCA1CA2LMNACYP1A2
SCHEMBL28451954 0.73 GABRA1 (0.48) FAAHCA1CA2LMNACYP1A2
SCHEMBL11884726 0.70 KMT2A (0.33) LMNACYP1A2
SCHEMBL38083 0.69
SCHEMBL11606150 0.69 CYP3A4 (0.44) FAAHCA1CA2LMNACYP1A2
SCHEMBL3229749 0.67 CYP3A4 (0.36) CYP3A4GABRA1TSHRSLC6A2GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11672876-B2 Imageable embolic microsphere BIOCOMPATIBLES UK LIMITED (GB) 2023-06-13 US claimed
EP-2968618-B1 IMAGEABLE EMBOLIC MICROSPHERE BIOCOMPATIBLES UK LTD (GB) 2021-02-17 EP claimed
CN-111569144-A Medicine-carrying embolism microsphere with developing function and preparation method thereof 科睿驰(深圳)医疗科技发展有限公司 2020-08-25 CN claimed
US-20200155711-A1 IMAGEABLE EMBOLIC MICROSPHERE Boston Scientific Medical Device Limited (IE) 2020-05-21 US claimed
US-20160030602-A1 IMAGEABLE EMBOLIC MICROSPHERE Boston Scientific Medical Device Limited (IE) 2016-02-04 US claimed
EP-3429627-B1 EMULSION COMPRISING PARTICLES Boston Scientific Medical Device Limited (IE) 2024-08-21 EP disclosed
CN-115137870-B Emulsion comprising particles 生物相容性英国公司 2024-05-10 CN disclosed
CN-117982687-A Imageable embolic microspheres 生物兼容英国有限公司 2024-05-07 CN disclosed
US-11672876-B2 Imageable embolic microsphere BIOCOMPATIBLES UK LIMITED (GB) 2023-06-13 US disclosed
CN-115137870-A Emulsions comprising particles 生物相容性英国公司 2022-10-04 CN disclosed
CN-108883189-B Emulsion comprising particles 生物相容性英国公司 2022-06-21 CN disclosed
EP-2968618-B1 IMAGEABLE EMBOLIC MICROSPHERE BIOCOMPATIBLES UK LTD (GB) 2021-02-17 EP disclosed
US-7790141-B2 Radio-opaque compounds, compositions containing same and methods of their synthesis and use PATHAK HOLDINGS, LLC (US) 2010-09-07 US disclosed
US-7790814-B2 Radiopaque polymers for circuit board assembly DELPHI TECHNOLOGIES, INC. (US) 2010-09-07 US disclosed
EP-1710265-B1 Radiopaque polymers for circuit board assembly DELPHI TECH INC (US) 2008-01-23 EP disclosed
EP-1710265-A1 Radiopaque polymers for circuit board assembly Delphi Technologies, Inc. (US) 2006-10-11 EP disclosed
US-20060222860-A1 Radiopaque polymers for circuit board assembly INTEL CORPORATION 2006-10-05 US disclosed
US-20050036946-A1 Radio-opaque compounds, compositions containing same and methods of their synthesis and use PATHAK HOLDINGS, LLC 2005-02-17 US disclosed
EP-0782564-A1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING AS (NO) 1997-07-09 EP disclosed
WO-1996009282-A1 IODINATED X-RAY CONTRAST MEDIA NYCOMED IMAGING A/S (NO) 1996-03-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160030602-A1 IMAGEABLE EMBOLIC MICROSPHERE MKI67, PCNA, VHL FAAH 2141/4885CA1 1993/4885CA2 3328/4885
US-11672876-B2 Imageable embolic microsphere MKI67, PCNA, VHL FAAH 2141/4885CA1 1993/4885CA2 3328/4885
US-20050036946-A1 Radio-opaque compounds, compositions containing same and methods of their synthesis and use PLOD3, IK, SON FAAH 2789/4885CA1 2512/4885CA2 4485/4885
US-20200155711-A1 IMAGEABLE EMBOLIC MICROSPHERE MKI67, PCNA, VHL FAAH 2141/4885CA1 1993/4885CA2 3328/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.