SCHEMBL2371297

SCHEMBL2371297

BrC(I)c1cccc(I)c1I

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29161089 0.81
SCHEMBL29161116 0.80 ALDH1A1 (0.34) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL3070445 0.76 FAAH (0.31) CYP1A2
SCHEMBL29406382 0.73 GABRA1 (0.48) ALDH1A1CYP1A2
SCHEMBL28451954 0.73 GABRA1 (0.48) ALDH1A1CYP1A2
SCHEMBL28449368 0.70 GABRA1 (0.39) CYP1A2
SCHEMBL38083 0.69
SCHEMBL3871873 0.67 ALDH1A1 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19
SCHEMBL7147429 0.67 TAAR1 (0.38)
SCHEMBL28773697 0.65 P2RX7 (0.36) ALDH1A1CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117586440-A Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-02-23 CN claimed
CN-117586440-B Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-04-09 CN disclosed
CN-117586440-A Iodinated polyhydroxy polymer, preparation method and liquid embolic agent prepared from iodinated polyhydroxy polymer 苏州美创医疗科技有限公司 2024-02-23 CN disclosed
EP-2545085-B1 Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof UNIVERSITÉ CLAUDE BERNARD LYON 1 UCBL (FR) 2016-10-19 EP disclosed
US-9434800-B2 Method of embolization using a radiopaque, non-biodegradable, water-insoluble iodinated benzyl ether of polyl(vinyl alcohol) ANTIA THERAPEUTICS S.A. (CH) 2016-09-06 US disclosed
US-20150335779-A1 Method of Embolization using a Radiopaque, Non-Biodegradable, Water-Insoluble Iodinated Benzyl Ether of PolyI(Vinyl Alcohol) ANTIA THERAPEUTICS S.A. (CH) 2015-11-26 US disclosed
US-9115230-B2 Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof ANTIA THERAPEUTICS S.A. (CH) 2015-08-25 US disclosed
US-20130108574-A1 RADIOPAQUE, NON-BIODEGRADABLE, WATER-INSOLUBLE IODINATED BENZYL ETHERS OF POLY(VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF MERIT MEDICAL SYSTEMS, INC. 2013-05-02 US disclosed
EP-2545085-A1 RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF Universite Claude Bernard Lyon 1 (UCBL) (FR) 2013-01-16 EP disclosed
WO-2011110589-A1 RADIOPAQUE, NON- BIODEGRADABLE, WATER - INSOLUBLE IODINATED BENZYL ETHERS OF POLY (VINYL ALCOHOL), PREPARATION METHOD THEREOF, INJECTABLE EMBOLIZING COMPOSITIONS CONTAINING THEREOF AND USE THEREOF UNIVERSITÉ CLAUDE BERNARD LYON 1 (UCBL) (FR) 2011-09-15 WO disclosed
EP-2365009-A1 Radiopaque, non-biodegradable, water-insoluble iodinated benzyl ethers of poly(vinyl alcohol), preparation method thereof, injectable embolizing compositions containing thereof and use thereof Universite Claude Bernard Lyon 1 (UCBL) (FR) 2011-09-14 EP disclosed