SCHEMBL30705705

SCHEMBL30705705

COC(=O)[C@@H]1[C@@H]2[C@H](CN1C(=O)Cc1cc(C)no1)C2(C)C

nearest known ligand 0.52

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
VHL P40337 6/20 0.52
CCNE1 P24864 9/20 0.40
CDK2 P24941 9/20 0.40
GSK3B P49841 7/20 0.40
ELOC Q15369 3/20 0.40
ELOB Q15370 3/20 0.40
POLB P06746 1/20 0.39
KMT2A Q03164 1/20 0.39
CDK1 P06493 1/20 0.39
CDK4 P11802 1/20 0.39
CCNA2 P20248 1/20 0.39
CCND1 P24385 1/20 0.39
CDK9 P50750 1/20 0.39
CDK6 Q00534 1/20 0.39
P2RX7 Q99572 2/20 0.39
EPHX2 P34913 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705637 0.88 VHL (0.51) VHLCCNE1CDK2GSK3BELOC
SCHEMBL30705671 0.86 VHL (0.39) VHLP2RX7EPHX2
SCHEMBL21696618 0.76 VHL (0.53) VHLCCNE1CDK2GSK3BPOLB
SCHEMBL30705635 0.75 VHL (0.38) VHLP2RX7EPHX2
SCHEMBL30705631 0.73 RXRA (0.34)
SCHEMBL32661830 0.72 VHL (0.51) VHLCCNE1CDK2GSK3BELOC
SCHEMBL8248147 0.72 MMP2 (0.33)
SCHEMBL24014601 0.70 FUCA1 (0.32)
SCHEMBL25757863 0.70 FUCA1 (0.32)
SCHEMBL29624408 0.70 MMP2 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS INC (US) 2026-01-15 US disclosed
EP-4539844-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION Trawsfynydd Therapeutics, Inc. (US) 2025-04-23 EP disclosed
CN-119604290-A Compounds for the treatment of coronavirus infections 特劳斯芬尼德治疗股份有限公司 2025-03-11 CN disclosed
WO-2023245166-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION ACE2, ACE, TMPRSS2 VHL 1899/4885CCNE1 1826/4885CDK2 790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.