SCHEMBL30705671

SCHEMBL30705671

COC(=O)[C@@H]1[C@@H]2[C@H](CN1C(=O)Cc1cc(C(F)(F)F)no1)C2(C)C

nearest known ligand 0.39

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
VHL P40337 2/20 0.39
PARG Q86W56 1/20 0.34
EPHX2 P34913 1/20 0.33
HDAC4 P56524 1/20 0.32
P2RX7 Q99572 2/20 0.32
LGMN Q99538 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30705635 0.90 VHL (0.38) VHLPARGEPHX2HDAC4P2RX7
SCHEMBL30705705 0.86 VHL (0.52) VHLEPHX2P2RX7
SCHEMBL30705637 0.75 VHL (0.51) VHLEPHX2P2RX7
SCHEMBL30705669 0.74 RXRA (0.33)
SCHEMBL30557045 0.71 IRAK4 (0.36) LGMN
SCHEMBL24235374 0.69 LGMN (0.47) LGMN
SCHEMBL25879033 0.69 CTSV (0.33)
SCHEMBL25076008 0.69 CTSV (0.33)
SCHEMBL8248147 0.68 MMP2 (0.33) LGMN
SCHEMBL24014601 0.67 FUCA1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS INC (US) 2026-01-15 US disclosed
EP-4539844-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION Trawsfynydd Therapeutics, Inc. (US) 2025-04-23 EP disclosed
CN-119604290-A Compounds for the treatment of coronavirus infections 特劳斯芬尼德治疗股份有限公司 2025-03-11 CN disclosed
WO-2023245166-A2 COMPOUNDS FOR TREATMENT OF A CORONAVIRUS INFECTION TRAWSFYNYDD THERAPEUTICS, INC. (US) 2023-12-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015337-A1 COMPOUNDS FOR TREATMENT A CORONAVIRUS INFECTION ACE2, ACE, TMPRSS2 VHL 1899/4885PARG 3431/4885EPHX2 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.