Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 7/20 | 0.46 |
| ▸ | CA2 | P00918 | 7/20 | 0.46 |
| ▸ | CA12 | O43570 | 6/20 | 0.46 |
| ▸ | CA9 | Q16790 | 6/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.39 |
| ▸ | STK17B | O94768 | 1/20 | 0.39 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 4/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7974876 | 0.84 | TDP1 (0.44) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL22905385 | 0.83 | CTSK (0.43) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL9067717 | 0.83 | TDP1 (0.53) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL28177271 | 0.83 | CTSK (0.43) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL4911352 | 0.83 | TDP1 (0.53) | MEN1GAAKMT2ATDP1MAOA | |
| SCHEMBL25379547 | 0.83 | CTSK (0.43) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL20122274 | 0.82 | CTSS (0.51) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL22518919 | 0.82 | CTSK (0.43) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL22518918 | 0.82 | CTSK (0.43) | MEN1GAAKMT2ATDP1CA1 | |
| SCHEMBL4909422 | 0.82 | NAALAD2 (0.40) | MEN1GAAKMT2ATDP1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |