Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA1 | P00915 | 5/20 | 0.38 |
| ▸ | CA2 | P00918 | 5/20 | 0.38 |
| ▸ | CA9 | Q16790 | 5/20 | 0.38 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.34 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 6/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8193725 | 0.85 | TDP1 (0.41) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL30705756 | 0.84 | MEN1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL22518918 | 0.79 | CTSK (0.43) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL22518919 | 0.79 | CTSK (0.43) | TDP1MEN1GAAKMT2ACA12 | |
| SCHEMBL8184855 | 0.79 | CTSS (0.38) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL8189424 | 0.79 | TDP1 (0.38) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7873171 | 0.79 | TDP1 (0.69) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7974877 | 0.78 | MAOA (0.38) | TDP1MEN1GAAKMT2AMAOA | |
| Trifluoroacetic Acid SCHEMBL20543049 | 0.78 | TDP1 (0.55) | TDP1MEN1GAAKMT2AMAOA | |
| SCHEMBL7059870 | 0.78 | MEN1 (0.42) | TDP1MEN1GAAKMT2ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001005748-A1 | OLIGOMERIC AMINO ACID DERIVATIVES USEFUL AS NITRIC OXIDE SYNTHASE INHIBITORS | MONSANTO COMPANY (US) | 2001-01-25 | — | — | WO | disclosed |