Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK2 | Q05397 | 5/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.40 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.40 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.38 |
| ▸ | TUBB | P07437 | 2/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.38 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.38 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.38 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.38 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30146986 | 0.76 | CYP2A6 (0.40) | PTK2CYP3A4CYP2A6CYP2E1CYP11B2 | |
| SCHEMBL16751046 | 0.76 | CYP2A6 (0.40) | PTK2CYP3A4CYP2A6CYP2E1CYP11B2 | |
| SCHEMBL30128217 | 0.71 | MAPT (0.33) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL30143991 | 0.68 | ALDH1A1 (0.46) | PTK2CYP11B2CYP11B1CYP19A1MAPT | |
| SCHEMBL30825856 | 0.67 | GAA (0.50) | PTK2CYP3A4CYP2A6CYP2E1TUBB4A | |
| SCHEMBL30406137 | 0.65 | CYP2A6 (0.50) | PTK2CYP3A4CYP2A6CYP2E1HTT | |
| SCHEMBL30186608 | 0.65 | TUBB1 (0.35) | TUBB4ATUBBTUBA3CTUBA1BTUBA4A | |
| SCHEMBL6844427 | 0.64 | CYP11B2 (0.54) | CYP3A4CYP11B2CYP17A1CYP11B1CYP19A1 | |
| SCHEMBL17067754 | 0.64 | ROCK1 (0.50) | PTK2CYP3A4CYP2A6CYP2E1CYP11B2 | |
| SCHEMBL28062496 | 0.64 | CYP19A1 (0.56) | CYP3A4CYP2A6CYP2E1CYP11B2CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111954525-B | Prodrugs of fused bicyclic C5aR antagonists | 凯莫森特里克斯股份有限公司 | 2023-12-26 | — | — | CN | disclosed |