Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.42 |
| ▸ | TUBB | P07437 | 1/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30827679 | 0.75 | CYP3A4 (0.45) | GAAALDH1A1CYP3A4CYP2A6CYP2E1 | |
| SCHEMBL30977140 | 0.73 | MAT2A (0.44) | GAAALDH1A1CYP3A4NPBWR1CYP1A2 | |
| SCHEMBL31456729 | 0.69 | CYP2A6 (0.53) | GAAALDH1A1CYP3A4CYP2A6CYP2E1 | |
| SCHEMBL4817184 | 0.68 | MAPK1 (0.51) | GAAALDH1A1KMT2ASMN1; SMN2LMNA | |
| SCHEMBL14992282 | 0.68 | ALDH1A1 (0.51) | ALDH1A1CYP3A4CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL31310093 | 0.67 | CYP2A6 (0.46) | GAAALDH1A1CYP3A4CYP2A6CYP2E1 | |
| SCHEMBL14911616 | 0.67 | ALOX12 (0.50) | GAACYP3A4CYP2A6CYP2E1HTT | |
| SCHEMBL30705774 | 0.67 | PTK2 (0.46) | GAAPTK2CYP3A4CYP2A6CYP2E1 | |
| SCHEMBL31456617 | 0.66 | CYP2A6 (0.53) | GAAALDH1A1CYP3A4CYP2A6CYP2E1 | |
| SCHEMBL31456679 | 0.66 | CYP3A4 (0.45) | GAAALDH1A1CYP3A4CYP2A6CYP2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4590396-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | Astrazeneca AB (SE) | 2025-07-30 | — | — | EP | disclosed |
| WO-2024062089-A1 | PCSK9 INHIBITORS AND METHODS OF USE THEREOF | ASTRAZENECA AB (SE) | 2024-03-28 | — | — | WO | disclosed |