SCHEMBL30709191

SCHEMBL30709191

Cc1ccc2c(c1)c1ccccc1n2-c1nc(-n2c3ccccc3c3cc(C)ccc32)c(-n2c3ccccc3c3cc(C)ccc32)c(-c2ccccc2-c2cccnc2)c1-n1c2ccccc2c2cc(C)ccc21

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 1/20 0.40
MAP2K4 P45985 1/20 0.39
CYP11B2 P19099 1/20 0.39
MAPK14 Q16539 1/20 0.38
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP2A6 P11509 1/20 0.37
PDE5A O76074 2/20 0.36
LMNA P02545 1/20 0.36
MAPT P10636 2/20 0.35
NPC1 O15118 2/20 0.35
TP53 P04637 2/20 0.35
RAB9A P51151 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
ELANE P08246 1/20 0.35
KDM4E B2RXH2 1/20 0.35
ALDH1A1 P00352 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30339697 0.91 CYP11B2 (0.41) CYP11B1MAP2K4CYP11B2MAOAMAOB
SCHEMBL30339764 0.91 CYP11B2 (0.41) CYP11B1MAP2K4CYP11B2MAOAMAOB
SCHEMBL20595685 0.91 CYP11B2 (0.41) CYP11B1MAP2K4CYP11B2MAOAMAOB
SCHEMBL23223249 0.91 CYP11B2 (0.41) CYP11B1MAP2K4CYP11B2MAOAMAOB
SCHEMBL30709266 0.90 CYP11B1 (0.44) CYP11B1CYP11B2MAPK14CYP2A6LMNA
SCHEMBL30709426 0.88 CYP11B1 (0.40) CYP11B1CYP11B2MAPK14MAPTALDH1A1
SCHEMBL30709213 0.88 MEN1 (0.43) MAPK14LMNAMAPTKDM4EALDH1A1
SCHEMBL30709336 0.87 CYP11B1 (0.44) CYP11B1CYP11B2MAPK14MAPTNPC1
SCHEMBL21888662 0.86 MAP2K4 (0.45) CYP11B1MAP2K4CYP11B2MAOAMAOB
SCHEMBL30339097 0.86 MAP2K4 (0.45) CYP11B1MAP2K4CYP11B2MAOAMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 CYP11B1 467/4885MAP2K4 4885/4885CYP11B2 244/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.