SCHEMBL30709273

SCHEMBL30709273

CC(C)(C)c1ccc2c(c1)c1ccccc1n2-c1nc(-n2c3ccccc3c3cc(C(C)(C)C)ccc32)c(-n2c3ccccc3c3cc(C(C)(C)C)ccc32)c(-c2ccccc2-c2ccc(-c3ccccc3)nc2-c2ccccc2)c1-n1c2ccccc2c2cc(C(C)(C)C)ccc21

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 3/20 0.31
NPY5R Q15761 1/20 0.31
TRPV1 Q8NER1 1/20 0.30
KIF11 P52732 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30709559 0.89 KDM4E (0.31)
SCHEMBL30709521 0.88 KDM4E (0.34) NPY5R
SCHEMBL30709451 0.87 MEN1 (0.33) DNMT1TRPV1
SCHEMBL30709635 0.85 KDM4E (0.36)
SCHEMBL30709642 0.84 ABCG2 (0.36) DNMT1TRPV1
SCHEMBL30709169 0.82 NPY5R (0.33) NPY5R
SCHEMBL30709583 0.80 CSF1R (0.34)
SCHEMBL30709277 0.80 DNMT1 (0.31) DNMT1
SCHEMBL30709537 0.80 KIF11 (0.36) DNMT1NPY5RKIF11
SCHEMBL30709611 0.80 DNMT1 (0.32) DNMT1KIF11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 DNMT1 1070/4885NPY5R 2303/4885TRPV1 444/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.