SCHEMBL30709385

SCHEMBL30709385

c1ccc(-c2cc(-c3ccccc3-c3c(-n4c5ccccc5c5ncccc54)c(-n4c5ccccc5c5ncccc54)nc(-n4c5ccccc5c5ncccc54)c3-n3c4ccccc4c4ncccc43)cc(-c3ccccc3)n2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TOP1 P11387 7/20 0.40
DHODH Q02127 5/20 0.34
CYP19A1 P11511 1/20 0.32
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 2/20 0.30
NPC1 O15118 1/20 0.30
SYK P43405 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
PDE4A P27815 1/20 0.30
PDE4C Q08493 1/20 0.30
PDE4D Q08499 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30709381 0.92 TOP1 (0.34) TOP1CYP19A1
SCHEMBL22148529 0.91 TOP1 (0.40) TOP1DHODHTSHRMAPK1HSD17B10
SCHEMBL30709517 0.89 TOP1 (0.38) TOP1DHODHTSHRMAPK1HSD17B10
SCHEMBL30709398 0.89 MEN1 (0.35) TOP1KDM4EALDH1A1LMNAMAPT
SCHEMBL22148776 0.89 SMN1; SMN2 (0.35) CYP19A1KDM4EALDH1A1LMNAMAPT
SCHEMBL30709490 0.89 SMN1; SMN2 (0.35) CYP19A1KDM4EALDH1A1LMNAMAPT
SCHEMBL30709339 0.86 CCR1 (0.35) KDM4ENPC1
SCHEMBL30709686 0.84 MAPK14 (0.40) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL30709477 0.84 PIK3CA (0.33) TOP1TSHRKDM4EALDH1A1
SCHEMBL22148726 0.84 TOP1 (0.34) TOP1DHODHTSHRMAPK1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 TOP1 2727/4885DHODH 962/4885CYP19A1 457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.