SCHEMBL30709686

SCHEMBL30709686

c1cncc(-c2ccccc2-c2c(-n3c4ccccc4c4ncccc43)c(-n3c4ccccc4c4ncccc43)nc(-n3c4ccccc4c4ncccc43)c2-n2c3ccccc3c3ncccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPK14 Q16539 1/20 0.40
CYP11B1 P15538 1/20 0.39
KDM4E B2RXH2 4/20 0.36
RAB9A P51151 3/20 0.36
NPC1 O15118 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
PDK2 Q15119 1/20 0.36
CKS1B P61024 3/20 0.36
SKP2 Q13309 3/20 0.36
CYP11B2 P19099 2/20 0.36
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
HPGD P15428 2/20 0.34
MEN1 O00255 1/20 0.34
POLB P06746 1/20 0.34
HTT P42858 1/20 0.34
KMT2A Q03164 1/20 0.34
GPR84 Q9NQS5 1/20 0.34
PDE10A Q9Y233 1/20 0.34
PIK3R2 O00459 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22148812 0.95 MAPK14 (0.37) MAPK14CYP11B1KDM4ERAB9ANPC1
SCHEMBL30709266 0.91 CYP11B1 (0.44) MAPK14CYP11B1KDM4ERAB9APDK2
SCHEMBL30709572 0.86 MAPK14 (0.41) MAPK14CYP11B1KDM4ERAB9APDK2
SCHEMBL22148892 0.86 MAPK14 (0.41) MAPK14CYP11B1KDM4ERAB9APDK2
SCHEMBL30709220 0.86 MAPK14 (0.41) MAPK14CYP11B1KDM4ERAB9APDK2
SCHEMBL22148761 0.86 MAPK14 (0.41) MAPK14CYP11B1KDM4ERAB9APDK2
SCHEMBL30709385 0.84 TOP1 (0.40) KDM4ENPC1ALDH1A1MAPTHPGD
SCHEMBL30709477 0.84 PIK3CA (0.33) KDM4EALDH1A1MEN1KMT2A
SCHEMBL22148527 0.84 CYP11B1 (0.38) MAPK14CYP11B1KDM4ERAB9ANPC1
SCHEMBL30709339 0.83 CCR1 (0.35) KDM4ENPC1L3MBTL1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11849634-B2 Composition of matter for use in organic light- emitting diodes KYULUX, INC. (JP) 2023-12-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11849634-B2 Composition of matter for use in organic light- emitting diodes NDUFV3, NDUFV2, CRY2 MAPK14 4682/4885CYP11B1 467/4885KDM4E 4409/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.