Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.35 |
| ▸ | CHRNA1 | P02708 | 7/20 | 0.35 |
| ▸ | CHRNB1 | P11230 | 7/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 7/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 7/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 7/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.35 |
| ▸ | CHRNG | P07510 | 5/20 | 0.35 |
| ▸ | CHRND | Q07001 | 5/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CCR1 | P32246 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30125098 | 0.93 | SLC6A3 (0.37) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL30124758 | 0.80 | CCR2 (0.35) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL30124641 | 0.79 | CCR2 (0.36) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL30710190 | 0.78 | CHRNA1 (0.31) | SLC6A3CHRNA1CHRNB1CHRNB2SLC6A2 | |
| SCHEMBL29987487 | 0.78 | TSHR (0.31) | SMN1; SMN2 | |
| SCHEMBL30710180 | 0.74 | KMT2A (0.36) | SLC6A3SLC6A2SLC6A4 | |
| SCHEMBL30124933 | 0.71 | HSD11B1 (0.31) | HSD11B1CCR2 | |
| SCHEMBL30124886 | 0.70 | PTPN1 (0.33) | CHRNA1CHRNB1CHRNB2SLC6A2CHRNB4 | |
| SCHEMBL30710205 | 0.70 | CRHBP (0.38) | — | |
| SCHEMBL30124913 | 0.68 | CA12 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403494-B | Method for synthesizing beta-hydroxy sulfone derivative by oxygen-initiated olefin double-functionalization under mild condition | 湘潭大学 | 2024-01-02 | — | — | CN | disclosed |