Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.38 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711157 | 0.82 | HDAC3 (0.39) | KDM4EALDH1A1LTB4RLTB4R2BRD4 | |
| SCHEMBL30684924 | 0.81 | PLK1 (0.50) | KDM4EALDH1A1LTB4RLTB4R2POLB | |
| SCHEMBL22061006 | 0.75 | ALDH1A1 (0.44) | KDM4EALDH1A1PTGDR2HTR6CMA1 | |
| SCHEMBL19410146 | 0.74 | SLC7A5 (0.38) | KDM4EALDH1A1BRD4HTR6 | |
| SCHEMBL1120727 | 0.73 | LMNA (0.46) | KDM4EALDH1A1TSHRHTTPOLB | |
| SCHEMBL30711151 | 0.72 | PPARG (0.55) | LTB4RLTB4R2HDAC6POLBHTR6 | |
| SCHEMBL16607258 | 0.72 | FPR2 (0.43) | — | |
| SCHEMBL19410228 | 0.70 | MTNR1A (0.33) | KDM4EALDH1A1BRD4HDAC6HTR6 | |
| SCHEMBL18953177 | 0.70 | KDM4E (0.44) | KDM4EALDH1A1BRD4TSHRHTT | |
| SCHEMBL24709934 | 0.70 | ALDH1A1 (0.40) | KDM4EALDH1A1NR1H2NR1H3HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110997698-B | Immunomodulatory agents acting as PD-1 antagonists | 百时美施贵宝公司 | 2023-12-26 | — | — | CN | disclosed |