Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 8/20 | 0.43 |
| ▸ | GABRD | O14764 | 8/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 8/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 8/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 8/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 8/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 8/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 8/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 8/20 | 0.43 |
| ▸ | GABRE | P78334 | 8/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 8/20 | 0.43 |
| ▸ | GABRG1 | Q8N1C3 | 8/20 | 0.43 |
| ▸ | GABRG3 | Q99928 | 8/20 | 0.43 |
| ▸ | GABRQ | Q9UN88 | 8/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31708196 | 0.90 | NPC1 (0.43) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31708151 | 0.85 | IGF1R (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31708084 | 0.82 | — | — | |
| SCHEMBL30712098 | 0.79 | HTR1D (0.39) | — | |
| SCHEMBL30712082 | 0.73 | MTNR1A (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30712083 | 0.73 | MTNR1A (0.53) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL31708181 | 0.73 | ALOX5 (0.39) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL12596191 | 0.72 | GPR84 (0.50) | TSHR | |
| SCHEMBL30276861 | 0.71 | ALOX5 (0.44) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL30712070 | 0.71 | GABRP (0.72) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4635492-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-10-22 | — | — | EP | disclosed |
| EP-4551212-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | Gilgamesh Pharmaceuticals, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024035757-A2 | TRYPTAMINES AND METHODS OF TREATING MOOD DISORDERS | GILGAMESH PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |