Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | PRCP | P42785 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30712598 | 1.00 | CA2 (0.38) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL30712600 | 0.82 | TDP1 (0.42) | SMN1; SMN2KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL30712573 | 0.82 | TDP1 (0.42) | SMN1; SMN2KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL445133 | 0.81 | SMN1; SMN2 (0.42) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL4563 | 0.81 | SMN1; SMN2 (0.42) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL4562 | 0.81 | SMN1; SMN2 (0.42) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL16106147 | 0.81 | SMN1; SMN2 (0.42) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL2909384 | 0.79 | AR (0.41) | CA2SMN1; SMN2BRD4KMT2AALDH1A1 | |
| SCHEMBL5031878 | 0.78 | CA2 (0.38) | CA2SMN1; SMN2BRD4KMT2AKDM4E | |
| SCHEMBL14831166 | 0.71 | TAAR1 (0.41) | BRD4KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119790041-A | Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2025-04-08 | — | — | CN | disclosed |
| CN-117402123-A | Alpha, beta-unsaturated amide compounds, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2024-01-16 | — | — | CN | disclosed |
| WO-2024008166-A1 | α,β-UNSATURATED AMIDE COMPOUND, AND PREPARATION METHOD THEREFOR, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海药物研究所 | 2024-01-11 | — | — | WO | disclosed |