SCHEMBL30712974

SCHEMBL30712974

N#CCC(=O)c1ccc(Cl)c(Cl)c1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.52
KMO O15229 3/20 0.51
HSD11B1 P28845 1/20 0.47
ABL1 P00519 1/20 0.47
HDAC3 O15379 2/20 0.46
HDAC4 P56524 2/20 0.46
HDAC1 Q13547 2/20 0.46
HDAC7 Q8WUI4 2/20 0.46
HDAC2 Q92769 2/20 0.46
HDAC10 Q969S8 2/20 0.46
HDAC11 Q96DB2 2/20 0.46
HDAC8 Q9BY41 2/20 0.46
HDAC6 Q9UBN7 2/20 0.46
HDAC9 Q9UKV0 2/20 0.46
HDAC5 Q9UQL6 2/20 0.46
SRD5A2 P31213 1/20 0.46
KDM4E B2RXH2 1/20 0.45
ALDH1A1 P00352 1/20 0.45
AGTR1 P30556 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133027 1.00 TSHR (0.52) TSHRKMOHSD11B1ABL1HDAC3
SCHEMBL12694460 0.86 HSP90AA1 (0.49) TSHRKMO
SCHEMBL31410597 0.84 KCNQ3 (0.42) ALDH1A1
SCHEMBL3589190 0.84 MAOA (0.41) TSHR
SCHEMBL8073597 0.82 KMO (0.49) TSHRKMOHSD11B1ABL1HDAC3
SCHEMBL11650138 0.80 KMO (0.50) TSHRKMOHSD11B1HDAC3HDAC4
SCHEMBL395103 0.80 GSK3B (0.48) ABL1KDM4EALDH1A1
SCHEMBL138022 0.79 GSK3B (0.57) TSHRKDM4EALDH1A1
SCHEMBL11649146 0.78 KMO (0.49) TSHRKMOHSD11B1HDAC3HDAC4
SCHEMBL9015106 0.78 TSHR (0.61) TSHRKMOHSD11B1HDAC3HDAC4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117285426-A Method for simultaneously preparing biphenyl bactericides and topramezone herbicide intermediates 帕潘纳(北京)科技有限公司 2023-12-26 CN disclosed