Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | VHL | P40337 | 1/20 | 0.50 |
| ▸ | ELOC | Q15369 | 1/20 | 0.50 |
| ▸ | ELOB | Q15370 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | METAP1 | P53582 | 1/20 | 0.40 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | PTPRC | P08575 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.36 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13135 | 1.00 | KDM4E (0.58) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL5956746 | 0.89 | KDM4E (0.47) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL69249 | 0.85 | VHL (0.64) | KDM4EHTTVHLELOCELOB | |
| Ethylene SCHEMBL8101571 | 0.82 | VHL (0.60) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL7992397 | 0.82 | KDM4E (0.48) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL2594793 | 0.81 | S100A4 (0.43) | KDM4EHTTS100A4METAP1PARP10 | |
| SCHEMBL29922129 | 0.81 | S100A4 (0.43) | KDM4EHTTS100A4METAP1PARP10 | |
| SCHEMBL2223886 | 0.78 | KDM4E (0.58) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL13938663 | 0.78 | KDM4E (0.58) | KDM4EHTTVHLELOCELOB | |
| SCHEMBL87314 | 0.78 | KDM4E (0.58) | KDM4EHTTVHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025136671-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| EP-4540230-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | Ensem Therapeutics, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023244710-A1 | ANILINO-PYRAZOLE DERIVATIVES, COMPOSITIONS AND METHODS THEREOF | ENSEM THERAPEUTICS, INC. (US) | 2023-12-21 | — | — | WO | disclosed |