Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.54 |
| ▸ | MPO | P05164 | 5/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | IAPP | P10997 | 1/20 | 0.47 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068210 | 0.89 | HSPA5 (0.48) | MTNR1AMPOSLC6A4IAPPHSPA5 | |
| SCHEMBL4071022 | 0.81 | MTNR1A (0.52) | MTNR1AMPONPSR1TAAR1NAMPT | |
| SCHEMBL28001335 | 0.81 | MTNR1A (0.52) | MTNR1AMPONPSR1NAMPTKDM4E | |
| SCHEMBL29191321 | 0.80 | IAPP (0.58) | MPOSLC6A4IAPPHSPA5MGLL | |
| Hydrochloric Acid SCHEMBL10786258 | 0.80 | MTNR1A (0.51) | MTNR1AMPONPSR1NAMPTHDAC3 | |
| SCHEMBL7117086 | 0.79 | CYP4F2 (0.49) | MPOSLC6A4IAPPMGLLTAAR1 | |
| SCHEMBL4371077 | 0.78 | AKR1B1 (0.61) | MPOHSPA5AKR1B1KDM4E | |
| SCHEMBL27530341 | 0.78 | TAAR1 (0.55) | MTNR1AMPOSLC6A4IAPPHSPA5 | |
| SCHEMBL1827150 | 0.78 | AKR1B1 (0.61) | MPOSLC6A4IAPPHSPA5MGLL | |
| SCHEMBL16797610 | 0.77 | CYP4F2 (0.46) | MPOSLC6A4IAPPHSPA5MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7842688-B2 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2010-11-30 | — | — | US | disclosed |
| US-7790715-B2 | Organic compounds | NOVARTIS AG (CH) | 2010-09-07 | — | — | US | disclosed |
| US-20090012055-A1 | Organic compounds | HEROLD PETER | 2009-01-08 | — | — | US | disclosed |
| EP-1961752-A2 | Piperidine Compounds | Speedel Experimenta AG (CH) | 2008-08-27 | — | — | EP | disclosed |
| US-20070010511-A1 | Organic compounds | NOVARTIS PHARMA AG (CH) | 2007-01-11 | — | — | US | disclosed |
| EP-1670760-A1 | ORGANIC COMPOUNDS | Speedel Experimenta AG (CH) | 2006-06-21 | — | — | EP | disclosed |
| WO-2005061457-A1 | ORGANIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2005-07-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090012055-A1 | Organic compounds | REN, ACE, ACE2 | MTNR1A 2695/4885MPO 296/4885SLC6A4 508/4885 |
| US-20070010511-A1 | Organic compounds | REN, ACE, ACE2 | MTNR1A 2695/4885MPO 296/4885SLC6A4 508/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.