Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.48 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.48 |
| ▸ | CLK2 | P49760 | 1/20 | 0.48 |
| ▸ | SRPK1 | Q96SB4 | 1/20 | 0.48 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.48 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | NOS1 | P29475 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409208 | 0.87 | ROCK2 (0.58) | MAOBDYRK1AMAP4K4CLK2CLK4 | |
| SCHEMBL2933207 | 0.81 | MAPT (0.68) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL30194367 | 0.81 | MAPT (0.68) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL260992 | 0.80 | ALDH1A1 (0.56) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL29365815 | 0.80 | ALDH1A1 (0.56) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL22259503 | 0.79 | GSK3B (0.56) | MAOBDYRK1ACLK2CLK4ROCK2 | |
| SCHEMBL21004185 | 0.79 | MAOB (0.52) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL22221023 | 0.79 | MAPK14 (0.47) | MAPTKDM4EALDH1A1DYRK1ACLK2 | |
| SCHEMBL20187143 | 0.78 | MAOB (0.58) | MAOBMAPTKDM4EALDH1A1DYRK1A | |
| SCHEMBL7378385 | 0.78 | MAOB (0.55) | MAOBMAPTKDM4EALDH1A1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117460508-A | Combination therapy comprising a METTL3 inhibitor and an additional anticancer agent | 斯托姆治疗有限公司 | 2024-01-26 | — | — | CN | disclosed |