⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL585157 | 0.77 | CYP11B1 (0.35) | — | |
| SCHEMBL3067329 | 0.74 | EPAS1 (0.35) | — | |
| SCHEMBL4643692 | 0.73 | ALDH1A1 (0.38) | — | |
| SCHEMBL27455229 | 0.70 | HTR2A (0.40) | — | |
| SCHEMBL18986893 | 0.69 | P2RX7 (0.37) | — | |
| SCHEMBL31722382 | 0.69 | P2RX7 (0.37) | — | |
| SCHEMBL17397762 | 0.69 | P2RX7 (0.37) | — | |
| SCHEMBL12584160 | 0.69 | P2RX7 (0.37) | — | |
| SCHEMBL4819283 | 0.68 | EPAS1 (0.33) | — | |
| SCHEMBL22012098 | 0.65 | PARP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8399490-B2 | Insecticides | SYNGENTA CROP PROTECTION LLC (US) | 2013-03-19 | — | — | US | disclosed |
| US-20100273830-A1 | NOVEL INSECTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-10-28 | — | — | US | disclosed |
| CN-101743237-A | condensed anthranilamide insecticides | SYNGENTA PARTICIPATIONS AG | 2010-06-16 | — | — | CN | disclosed |
| EP-2167484-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | Syngeta Participations AG (CH) | 2010-03-31 | — | — | EP | disclosed |
| WO-2009010260-A2 | CONDENSED ANTHRANILAMIDE INSECTICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2009-01-22 | — | — | WO | disclosed |