Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4824033 | 0.88 | ACHE (0.41) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL4825340 | 0.76 | IL1RN (0.36) | — | |
| SCHEMBL4826780 | 0.74 | PARP1 (0.31) | — | |
| SCHEMBL4842396 | 0.74 | ACHE (0.37) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL9886292 | 0.71 | GID4 (0.45) | CYP1A2CYP2C9KCNH2 | |
| SCHEMBL4641247 | 0.71 | GID4 (0.45) | CYP1A2CYP2C9KCNH2 | |
| SCHEMBL4643692 | 0.71 | ALDH1A1 (0.38) | CYP1A2CYP2C9TSHRALDH1A1NR3C1 | |
| SCHEMBL8055338 | 0.68 | EPAS1 (0.37) | EPAS1ACHE | |
| SCHEMBL3071652 | 0.68 | — | — | |
| SCHEMBL4823275 | 0.68 | ADRA1A (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | claimed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | claimed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | claimed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-7396369-B2 | 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2008-07-08 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | L'OREAL S.A. (FR) | 2007-01-18 | — | — | US | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
| EP-1739073-A1 | New primary 2,3-disubstituted para-phenylendiamins and their use as oxidative colouring of keratinic fibers | L'Oréal (FR) | 2007-01-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070011823-A1 | Novel 2,3-disubstituted primary para-phenylenediamines and process for oxidation dyeing of keratin fibers | KRT18, VIM, CDC73 | EPAS1 1827/4885CYP1A2 763/4885CYP2C9 1284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.