Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 7/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.40 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | FLT1 | P17948 | 1/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20550796 | 0.83 | ALDH1A1 (0.47) | KMT2ALMNANPC1HTTTP53 | |
| SCHEMBL7096179 | 0.80 | KMT2A (0.44) | MEN1KMT2ALMNASMN1; SMN2TP53 | |
| SCHEMBL11904301 | 0.79 | KMT2A (0.41) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL30716683 | 0.77 | PTGS2 (0.41) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL18058991 | 0.77 | PTGS2 (0.41) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL5653976 | 0.77 | PTGS2 (0.41) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL4798350 | 0.75 | KMT2A (0.44) | MEN1KMT2ACA2ALDH1A1 | |
| SCHEMBL4801052 | 0.75 | ALDH1A1 (0.42) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL18041967 | 0.74 | SMN1; SMN2 (0.42) | MEN1KMT2ALMNANPC1HTT | |
| SCHEMBL4983476 | 0.74 | CYP2D6 (0.51) | LMNANPC1HTTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111936496-B | Heterocyclic compounds useful as medicaments | 马萨里克大学 | 2023-12-29 | — | — | CN | disclosed |