Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7096179 | 0.84 | KMT2A (0.44) | ALDH1A1LMNAKMT2AEGFRERBB2 | |
| SCHEMBL4801052 | 0.84 | ALDH1A1 (0.42) | ALDH1A1LMNAMAPTKMT2ANPC1 | |
| SCHEMBL4798350 | 0.84 | KMT2A (0.44) | ALDH1A1KDM4EKMT2AEGFRERBB2 | |
| SCHEMBL4983476 | 0.84 | CYP2D6 (0.51) | ALDH1A1LMNAMAPTHTTRECQL | |
| SCHEMBL30716686 | 0.83 | MEN1 (0.44) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL19716790 | 0.77 | ENPP3 (0.43) | ALDH1A1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL19716788 | 0.77 | ENPP3 (0.43) | ALDH1A1LMNAKDM4EMAPTKMT2A | |
| SCHEMBL11218064 | 0.76 | SRC (0.47) | ALDH1A1LMNAMAPK1GAA | |
| SCHEMBL11212883 | 0.76 | SRC (0.47) | ALDH1A1LMNAMAPTKMT2AHTT | |
| SCHEMBL11812541 | 0.75 | LMNA (0.54) | ALDH1A1LMNARXFP1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3619204-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | The University of Melbourne (AU) | 2020-03-11 | — | — | EP | disclosed |
| WO-2018201192-A1 | COMPOUNDS FOR THE TREATMENT OF RESPIRATORY DISEASES | THE UNIVERSITY OF MELBOURNE (AU) | 2018-11-08 | — | — | WO | disclosed |