SCHEMBL30717852

SCHEMBL30717852

CC(C)[C@H](NC(=O)CNC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 11/20 0.50
▸ OPRM1 P35372 6/20 0.50
▸ OPRK1 P41145 1/20 0.50
▸ TFPI P10646 1/20 0.48
▸ CCKBR P32239 2/20 0.46
▸ IL23R Q5VWK5 2/20 0.46
▸ CCKAR P32238 1/20 0.46
▸ CHRNA1 P02708 1/20 0.46
▸ CHRNG P07510 1/20 0.46
▸ CHRNB1 P11230 1/20 0.46
▸ CHRND Q07001 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717906 0.98 OPRD1 (0.53) OPRD1OPRM1OPRK1TFPICCKBR
SCHEMBL30717908 0.96 IL23R (0.48) OPRD1OPRM1OPRK1TFPIIL23R
SCHEMBL30717895 0.95 OPRD1 (0.49) OPRD1OPRM1OPRK1CCKBRIL23R
SCHEMBL30717888 0.94 OPRD1 (0.56) OPRD1OPRM1OPRK1CCKBRCCKAR
SCHEMBL30717886 0.93 OPRD1 (0.51) OPRD1OPRM1OPRK1CCKBRIL23R
SCHEMBL30717830 0.93 OPRD1 (0.52) OPRD1OPRM1OPRK1TFPICCKBR
SCHEMBL30717859 0.92 OPRD1 (0.50) OPRD1OPRM1OPRK1CCKBRIL23R
SCHEMBL30717863 0.92 TFPI (0.52) OPRK1TFPIIL23R
SCHEMBL30717828 0.91 OPRD1 (0.51) OPRD1OPRM1OPRK1IL23R
SCHEMBL30717867 0.91 TFPI (0.46) TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP OPRD1 4807/4885OPRM1 4813/4885OPRK1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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