SCHEMBL30717886

SCHEMBL30717886

C[C@H](NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)NCC(=O)N[C@H](C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ OPRD1 P41143 17/20 0.51
▸ OPRM1 P35372 9/20 0.51
▸ OPRK1 P41145 2/20 0.51
▸ IL23R Q5VWK5 1/20 0.46
▸ CCKAR P32238 3/20 0.45
▸ CCKBR P32239 3/20 0.45
▸ OPRL1 P41146 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717859 0.99 OPRD1 (0.50) OPRD1OPRM1OPRK1IL23RCCKAR
SCHEMBL30717895 0.98 OPRD1 (0.49) OPRD1OPRM1OPRK1IL23RCCKAR
SCHEMBL30717849 0.96 OPRD1 (0.52) OPRD1OPRM1OPRK1OPRL1
SCHEMBL30717828 0.96 OPRD1 (0.51) OPRD1OPRM1OPRK1IL23ROPRL1
SCHEMBL30717908 0.96 IL23R (0.48) OPRD1OPRM1OPRK1IL23R
SCHEMBL30717861 0.95 OPRD1 (0.51) OPRD1OPRM1OPRK1IL23R
SCHEMBL30717880 0.94 OPRD1 (0.52) OPRD1OPRM1OPRK1IL23R
SCHEMBL30717877 0.94 F2 (0.45) OPRD1OPRM1IL23R
SCHEMBL30717879 0.94 F2 (0.45) OPRD1OPRM1IL23R
SCHEMBL30717885 0.94 F2 (0.45) OPRD1OPRM1IL23R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP OPRD1 4807/4885OPRM1 4813/4885OPRK1 4852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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