SCHEMBL30717877

SCHEMBL30717877

C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)N[N+](=O)[O-])C(=O)N[C@H](C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O)[C@@H](C)O

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ F2 P00734 2/20 0.45
▸ BACE1 P56817 1/20 0.44
▸ BACE2 Q9Y5Z0 1/20 0.44
▸ GNPAT O15228 1/20 0.44
▸ OPRM1 P35372 1/20 0.43
▸ OPRD1 P41143 1/20 0.43
▸ CDYL2 Q8N8U2 1/20 0.43
▸ CDYL Q9Y232 1/20 0.43
▸ IL23R Q5VWK5 1/20 0.43
▸ CHRNA1 P02708 1/20 0.43
▸ CHRNG P07510 1/20 0.43
▸ CHRNB1 P11230 1/20 0.43
▸ CHRND Q07001 1/20 0.43
▸ SSTR3 P32745 1/20 0.42
▸ CASP1 P29466 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30717879 1.00 F2 (0.45) F2BACE1BACE2GNPATOPRM1
SCHEMBL30717885 1.00 F2 (0.45) F2BACE1BACE2GNPATOPRM1
SCHEMBL30717848 0.97 OPRM1 (0.44) F2BACE1BACE2OPRM1OPRD1
SCHEMBL30717897 0.97 OPRM1 (0.44) F2BACE1BACE2OPRM1OPRD1
SCHEMBL30717911 0.95 KISS1R (0.47) BACE1BACE2OPRM1OPRD1
SCHEMBL30717856 0.95 IL23R (0.49) F2BACE1BACE2IL23R
SCHEMBL30717850 0.95 IL23R (0.49) F2BACE1BACE2IL23R
SCHEMBL30717882 0.95 IL23R (0.49) F2BACE1BACE2IL23R
SCHEMBL30717859 0.94 OPRD1 (0.50) OPRM1OPRD1IL23R
SCHEMBL30717895 0.94 OPRD1 (0.49) OPRM1OPRD1IL23RCHRNA1CHRNG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263393-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-08-21 — — US disclosed
EP-4590664-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-07-30 — — EP disclosed
WO-2025055942-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
WO-2025055943-A1 INHIBITORS OF PROSTATE SPECIFIC MEMBRANE ANTIGEN AND USE THEREOF SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2025-03-20 — — WO disclosed
EP-4511367-A1 FAP INHIBITORS Shanghai Sinotau Biotech. Co., Ltd (CN) 2025-02-26 — — EP disclosed
WO-2024022332-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2024-02-01 — — WO disclosed
WO-2023202655-A1 FAP INHIBITORS SHANGHAI SINOTAU BIOTECH. CO., LTD (CN) 2023-10-26 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263393-A1 FAP INHIBITORS FAP, APC, FIBP F2 508/4885BACE1 254/4885BACE2 238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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