Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK1 | P23458 | 12/20 | 0.40 |
| ▸ | JAK3 | P52333 | 8/20 | 0.40 |
| ▸ | BTK | Q06187 | 3/20 | 0.39 |
| ▸ | JAK2 | O60674 | 12/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30718319 | 0.91 | JAK1 (0.40) | JAK1JAK3BTKJAK2SIGMAR1 | |
| SCHEMBL27297561 | 0.81 | JAK1 (0.40) | JAK1JAK3BTKJAK2 | |
| SCHEMBL30718308 | 0.81 | JAK1 (0.40) | JAK1JAK3BTKJAK2 | |
| SCHEMBL27289337 | 0.81 | JAK1 (0.41) | JAK1JAK3JAK2 | |
| SCHEMBL24840031 | 0.81 | SIGMAR1 (0.40) | JAK3JAK2SIGMAR1 | |
| SCHEMBL29189103 | 0.81 | SIGMAR1 (0.40) | JAK3JAK2SIGMAR1 | |
| SCHEMBL31359742 | 0.81 | SIGMAR1 (0.40) | JAK3JAK2SIGMAR1 | |
| SCHEMBL30718307 | 0.79 | JAK1 (0.41) | JAK1JAK3JAK2 | |
| SCHEMBL30718309 | 0.79 | JAK1 (0.41) | JAK1JAK3JAK2 | |
| SCHEMBL30718302 | 0.75 | JAK1 (0.38) | JAK1JAK3BTKJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024006559-A1 | MODULATORS OF NLRP3 INFLAMMASOME AND RELATED PRODUCTS AND METHODS | Neumora Therapeutics, Inc. (US) | 2024-01-04 | — | — | WO | disclosed |