Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.40 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 8/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OGFRL1 | Q5TC84 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | CACNG2 | Q9Y698 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15135220 | 0.81 | HTR2C (0.45) | KDM4EALDH1A1 | |
| SCHEMBL30719404 | 0.76 | JAK2 (0.53) | KDM4EMAPTALDH1A1LMNAPOLB | |
| SCHEMBL30719403 | 0.75 | PDE10A (0.44) | GRIA1PIK3CAMTOR | |
| SCHEMBL5237091 | 0.73 | HRH4 (0.47) | POLB | |
| SCHEMBL14858605 | 0.73 | LMNA (0.47) | KDM4EPIK3CAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL10094631 | 0.72 | HSD11B1 (0.46) | KDM4EPRKCHPRKCEGRIA1PIK3CA | |
| SCHEMBL14377416 | 0.72 | GRIN2D (0.55) | KDM4EPRKCHPRKCEGRIA1PIK3CA | |
| SCHEMBL10512926 | 0.71 | KDM4E (0.41) | KDM4EPRKCHPRKCEGRIA1PIK3CA | |
| SCHEMBL20953955 | 0.70 | KDM4E (0.55) | KDM4EPRKCHPRKCEPIK3CAOPRM1 | |
| SCHEMBL5233190 | 0.70 | CYP3A4 (0.39) | KDM4EMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112513020-B | KDM1A inhibitors for the treatment of diseases | 伊美格生物科学公司 | 2024-02-23 | — | — | CN | disclosed |